1. SP3494EN-L/TR Substitution Conclusion The SP3494EN-L/TR is compatible with the original part in terms of fundamental interface and power supply. However, significant differences in data rate and noise margin determine that it is not a direct drop-in replacement and must be carefully evaluated based on the application context. The key differences are: 1. Higher data rate (2.5 Mbps vs. 250 kbps). While this is an advantage for high-speed communication applications, it may introduce signal integrity issues or unnecessary cost overhead in systems originally designed for low-speed operation. 2. Lower receiver hysteresis (20 mV vs. 100 mV). This directly and substantially weakens the chip's noise immunity—its ability to correctly interpret logic states in the presence of common-mode noise or signal jitter. In electrically noisy industrial environments, this significantly increases the risk of communication bit errors, making it the most critical weakness to consider during substitution.