1. 74FCT16245ETPAG Substitution Conclusion From the perspective of core electrical parameters and functionality, the 74FCT16245ETPAG can directly replace the original part CY74FCT16245ATPVC. Both are non-inverting, 2‑group 8‑bit, tri‑state transceivers, with identical supply voltage range (4.5 V to 5.5 V) and drive capability (output high/low current 32 mA/64 mA), ensuring high functional compatibility. The primary difference lies in the package dimensions: the original device uses a 48‑BSSOP (width 7.50 mm), while the substitute is offered in a 48‑TSSOP (width 6.10 mm). The replacement package is approximately 1.4 mm narrower; therefore, direct substitution requires verification of PCB pad compatibility. If the original layout was designed for BSSOP dimensions, installing the TSSOP directly may result in poor solder contact or necessitate trace adjustments. Conversely, if sufficient clearance exists or the pad design accommodates the smaller package, the replacement can be seamless. Additionally, the manufacturer has changed from Texas Instruments (TI) to Renesas. It is advisable to validate in the actual application whether dynamic parameters—such as propagation delay and noise margin—fully match. However, given that both devices adhere to the same FCT logic family standard, they typically meet the requirements for general industrial‑grade applications.