1. Substitution Conclusion for 74FCT16245ETPAG The 74FCT16245ETPAG can directly replace the original part CY74FCT16245TPVC in terms of core electrical parameters and functionality. Both are non-inverting, 2-element × 8-bit tri-state transceivers with identical drive current (32mA/64mA) and supply voltage range (4.5V to 5.5V). The primary difference lies in the package footprint: the original device is in a 48-BSSOP package (width 7.50mm), whereas the substitute is in a 48-TFSOP package (width 6.10mm). The narrower package of the substitute may lead to incompatibility with the original PCB pad layout, so package compatibility must be verified. If the package is confirmed to be compatible or design adjustments are permissible, the substitution can achieve full functional and performance equivalence.