SP3078EEN-L Substitution Conclusion From a technical specification standpoint, the SP3078EEN-L can serve as a replacement for the SN75HVD10D, though careful evaluation of application constraints is required. Key differences include: lower receiver hysteresis (15 mV vs. 35 mV), which implies reduced noise immunity and a higher risk of bit errors in noisy environments; lower data rate capability (16 Mbps vs. 32 Mbps), effectively halving the maximum communication speed and making it unsuitable for systems requiring high‑speed data transfer; and a fixed supply voltage (3.3V only vs. a 3V–3.6V range), resulting in tighter supply tolerance and a requirement for a precise 3.3V source. Substitution may be acceptable in applications where noise sensitivity is low, data rates remain below 16 Mbps, and the power supply is stable. However, for high‑reliability or high‑speed designs, direct replacement is not recommended. SP3078EEN-L/TR Substitution Conclusion The SP3078EEN-L/TR shares identical electrical specifications with the SP3078EEN-L; therefore, the substitution feasibility conclusion remains the same. Note that the “/TR” suffix indicates tape‑and‑reel packaging, which is suited for automated assembly. Compared to the SN75HVD10D, the differences are: lower receiver hysteresis (15 mV vs. 35 mV), leading to degraded noise rejection and potential signal integrity issues; lower data rate (16 Mbps vs. 32 Mbps), limiting throughput and making it inadequate for high‑speed applications; and a fixed 3.3V supply (vs. a 3V–3.6V range), offering less supply flexibility and requiring strict compatibility with 3.3V systems. Replacement is acceptable under conditions of low speed, stable power, and low‑noise environments. Otherwise, the original part should be preferred.