1. ADM3078EYRZ-REEL7 Substitution Conclusion The ADM3078EYRZ-REEL7 can serve as a drop-in replacement for the original SP3078EMN-L/TR, as both devices are fully compatible in terms of data rate (16 Mbps), package (8‑SOIC), and core functionality (half‑duplex RS‑422/RS‑485 transceiver), ensuring direct pin‑to‑pin and electrical interface substitution. Key differences include: receiver hysteresis of 100 mV (versus 15 mV for the original), which provides improved noise immunity in electrically noisy industrial environments but may slightly reduce sensitivity to weak signals; and a supply voltage range of 3 V to 3.6 V (compared to the original’s nominal 3.3 V specification), which fully covers the original voltage requirement and ensures stable operation in standard 3.3 V systems—though it is necessary to verify whether the original design relies critically on the low‑hysteresis characteristic. Overall, substitution is viable in applications with higher ambient noise or where supply voltage may vary moderately. However, if the original system depends on low hysteresis for precise signal detection, the potential performance impact should be evaluated.