1. Configuration Data Storage Mechanism: The MCP48FEB18-16E/ST integrates internal EEPROM, whereas the MCP48FVB18-16E/ST utilizes volatile memory. This represents a fundamental architectural difference. The EEPROM-equipped variant (FEB) retains user configuration (e.g., output channel gain, shutdown state, and DAC register values) after power loss, automatically restoring to the preset state upon power-up, thereby enabling "power-on ready" operation. In contrast, the volatile variant (FVB) requires its configuration and output to be rewritten via SPI by the host controller after each power cycle; otherwise, it remains in an indeterminate state. 2. Application Scenarios and System Design Impact: MCP48FEB18-16E/ST (EEPROM): Suitable for systems demanding deterministic power-on behavior, aiming to reduce MCU initialization code/communication overhead, or requiring the DAC to output a specific safe value before the host controller is ready. Its design simplifies software but increases unit cost. MCP48FVB18-16E/ST (Volatile): Applicable where output values are managed dynamically and in real-time by the host controller, or in cost-sensitive systems where a power-on initialization sequence is acceptable. It relies on the system's software and power sequencing design to ensure proper startup.