1. Conclusion on LM6144BIM/NOPB Substitution Direct substitution is not recommended. There are significant differences between the LM6144BIM/NOPB and the OPA4350UA/2K5 in key parameters. The LM6144BIM/NOPB exhibits an input bias current (174 nA vs. 0.5 pA) three orders of magnitude higher, an input offset voltage (1.3 mV vs. 150 µV) nearly ten times larger, and a lower gain-bandwidth product (18 MHz vs. 38 MHz). Consequently, its DC accuracy and high-frequency response are substantially inferior to the original part. It is likely unsuitable for applications demanding low input error and high bandwidth, such as high-impedance sensing, precision measurement, or wideband signal processing. While it offers a wider supply range (1.8-24 V) and lower quiescent current (750 µA vs. 5.2mA), making it attractive for low-power, wide-supply scenarios, the core performance discrepancies may degrade system accuracy or stability. 2. Conclusion on LM6144AIM/NOPB Substitution Direct substitution is similarly not recommended. The LM6144AIM/NOPB's specifications are essentially identical to those of the LM6144BIM/NOPB. Therefore, the comparison conclusion against the OPA4350UA/2K5 remains the same: its high input bias current (174 nA), large offset voltage (1.3 mV), and lower gain-bandwidth product (18 MHz) will severely limit its applicability in precision or high-speed circuits. It is particularly unsuitable for applications requiring CMOS-level input impedance (pA-range bias current) or microvolt-level error correction. Although its wide-voltage and low-power characteristics are advantageous in general-purpose scenarios, direct replacement may lead to performance shortfalls if the original design relies on the OPA4350's high precision and bandwidth.