1. TS272ACDT Substitution Conclusion The TS272ACDT can serve as a drop‑in replacement for the TLC252ACD in most applications, with one critical limitation: its minimum operating voltage is 3 V, whereas the TLC252ACD can operate down to 1.4 V. Consequently, the TS272ACDT is not suitable for ultra‑low‑voltage applications such as 1.8 V systems or single‑cell battery supplies. In other respects, the TS272ACDT offers clear performance advantages: - Higher slew rate (5.5 V/µs vs. 2.9 V/µs) and gain‑bandwidth product (3.5 MHz vs. 2.2 MHz), resulting in faster dynamic response. - Lower quiescent current (1 mA per channel vs. 1.9 mA), improving power efficiency. - Well‑specified output current capability (45 mA), providing stronger load‑driving capacity. The package is fully compatible, and key parameters such as input bias current and offset voltage are equivalent. Provided the system supply voltage is ≥3 V and the ultra‑low‑voltage capability of the original part is not required, the TS272ACDT represents a suitable performance‑enhancing substitute.