1. Linearity vs. Output Power Trade-off: The LT5572 offers a higher P1dB (9.3 dBm vs. 7.9 dBm), providing superior linearity and lower distortion when handling complex modulation signals (e.g., high-PAPR OFDM signals). However, its nominal output power (1.4 dBm) is significantly lower than that of the LT5528 (4 dBm). This indicates a likely difference in the internal amplifier's bias point or architecture; the LT5572 appears to sacrifice some output power to optimize linearity. Post-substitution, re-adjustment of the subsequent gain distribution in the signal chain may be necessary. 2. Noise Performance & Current Consumption: The LT5572 exhibits a slightly higher noise floor (-158.6 dBm/Hz vs. -159 dBm/Hz) and a significantly increased operating current (145 mA vs. 125 mA). This suggests that to achieve higher linearity, it likely employs a higher bias current or a different circuit topology, resulting in increased overall power dissipation and thermal load. This has minor implications for system power supply and thermal design. 3. Performance vs. Frequency Response: The LT5528's key parameters (P1dB, Noise Floor) are specified across the full 1.5-2.4 GHz band, whereas the LT5572's test frequency is specified only at 2 GHz. The LT5572's nominally superior performance (e.g., high P1dB) may be optimal only at the band center. Performance may degrade towards the band edges, particularly near the 2.5 GHz upper limit. It is crucial to verify that performance meets requirements across the entire target operating band before substitution. Summary: Feasibility hinges on the application's core requirements. If the system demands stringent linearity and distortion immunity, and can accommodate the reduced output power with subsequent gain chain adjustments, the LT5572 may be considered. If the system is more sensitive to output power, overall power consumption, and flat performance across a wide bandwidth, the original LT5528 design should be retained. A direct replacement risks failing to meet system link budget or linearity specifications.