1. ADA4622-2ARMZ-R7 Substitution Conclusion The ADA4622-2ARMZ-R7 outperforms the original OPA2172IDGKR in most key parameters; however, attention should be paid to its output drive capability and minimum operating voltage limitations. Compared to the OPA2172, the ADA4622-2ARMZ-R7 employs J‑FET inputs, offering lower input bias current (2 pA vs. 8 pA) and superior input offset voltage (40 µV vs. 200 µV). This enables higher accuracy and lower input error in applications such as high‑impedance sensor signal conditioning and precision measurement. Additionally, its higher slew rate (23 V/µs vs. 10 V/µs) makes it suitable for scenarios requiring fast transient response. On the downside, its output current is lower (20 mA vs. 75 mA), resulting in weaker ability to drive capacitive or low‑impedance loads, and its minimum operating voltage is higher (5 V vs. 4.5 V), which may limit use in low‑voltage supply systems. If the application prioritizes precision, speed, and power efficiency (lower quiescent current) over output drive capability, and the supply voltage is ≥5 V, the ADA4622-2ARMZ-R7 can serve as a high‑performance replacement.