1. SN65LBC176ADRG4 Substitution Conclusion From a functional and package perspective, the SN65LBC176ADRG4 can directly replace the LTC1481IS8. Both are half-duplex, 1/1 RS-422/485 transceivers, utilizing the same 8-SOIC package and 5V supply. The differences lie in the data rate and receiver hysteresis: the SN65LBC176ADRG4 supports up to 30 Mbps (versus 2.5 Mbps for the LTC1481) and features 50 mV of receiver hysteresis (slightly higher than the LTC1481’s 45 mV). The higher data rate makes it suitable for higher-speed communication scenarios while maintaining backward compatibility with lower-speed applications. The minor hysteresis difference has a limited impact on noise margin and typically does not affect normal operation. However, it should be noted that the high-speed performance may be more sensitive to PCB layout and cable matching; signal integrity should be evaluated in low-speed, long-line applications. If the system has no specific speed requirements and operates in typical noise environments, this part can be considered a high-performance drop-in replacement.